San Lorenzo vs. Estudiantes (Tuesday, 11.00pm)
San Lorenzo will be hoping to book their place in the next round of the Copa Sudamericana when they host Estudiantes Merida at the Estadio Pedro Bidegain on Tuesday evening.
The hosts need to win, and hope results elsewhere go in their favour to stand any chance of finishing in second place, while the visitors have already been mathematically knocked out of the competition.
We say: San Lorenzo 1-0 Estudiantes Merida
Considering Estudiantes Merida have already been eliminated from the competition, they may not be as motivated as their opponents, who still have a chance of qualifying for the next round.
As such, we expect San Lorenzo to eke out a victory, however, given their recent struggles in front of goal, it is unlikely to be a high-scoring game.
Palestino vs. Fortaleza (Tuesday, 11.00pm)
Palestino take on Fortaleza at the Estadio Municipal La Cisterna on Tuesday evening, in their final Copa Sudamericana group stage game.
The hosts need just one point to qualify for the next round, while the visitors have already confirmed their place in the round of 16 as group winners.
We say: Palestino 1-1 Fortaleza
Tuesday's game is far more important to Palestino, and we expect them to book their place in the next round of the Copa Sudamericana by picking up a point.
While Fortaleza have been very impressive in the competition up to this point, they did struggle in their last away match, against Estudiantes Merida.
Sao Paulo vs. Tigre (Wednesday, 1.30am)
Heading into the final group stage encounter at the Copa Sudamericana, Sao Paulo and Tigre are already assured of a spot in the round of 16 when they square off at Estadio Cicero Pompeu de Toledo on Tuesday.
A 2-1 win over Academia Puerto Cabello on matchday five secured the Argentines' place in the knockout round, while Tricolor Paulista are undefeated in the group stage, coming away with an emphatic 5-0 triumph versus Deportes Tolima the last time out.
We say: Sao Paulo 1-0 Tigre
With first place basically assured, Sao Paulo will want to get through this match without any serious injuries, so we do not expect this to be a very intense game.
However, the overall depth of Tricolor Paulista along with a solid defensive shape should be enough for them to claim a narrow victory against an opponent in Tigre who are struggling away from home.
Tolima vs. Puerto Cabello (Wednesday, 1.30am)
Deportes Tolima and Academia Puerto Cabello only have pride to play for when the two sides square off in their final group stage encounter at the Copa Sudamericana on Tuesday at Estadio Manuel Murillo Toro in Colombia.
El Vinotinto y Oro were officially eliminated from this competition when they were beaten 5-0 by Sao Paulo on matchday five, while the Venezuelans are without a point in this edition of the tournament, falling 2-1 at Tigre in their previous encounter.
We say: Deportes Tolima 1-0 Academia Puerto Cabello
These are two defensive-minded teams with nothing to play for, and we anticipate a close game with the Colombians' experience in big tournaments and overall quality narrowly coming out on top.