Imanol Alguacil's men sit three points clear at the top of the section and will progress as group winners if the Red Devils fail to win by two or more goals, and here Sports Mole rounds up the team news for both clubs.
REAL SOCIEDAD vs. MANCHESTER UNITED
REAL SOCIEDAD
Out: Martin Merquelanz (knee), Mikel Oyarzabal (cruciate ligament), Mohamed-Ali Cho (hamstring), Umar Sadiq (ACL), David Silva (thigh), Ander Martin (knee)
Doubtful: Ander Barrenetxea (hamstring), Aihen Munoz (adductor), Takefusa Kubo (shoulder), Alex Sola (knee)
Sports Mole's predicted XI: Remiro; Gorosabel, Zubeldia, Pacheco, Rico; Merino, Zubimendi, Guevara; Mendez; Sorloth, Fernandez
MANCHESTER UNITED
Out: Raphael Varane (thigh), Mason Greenwood (club suspension), Axel Tuanzebe (unspecified), Brandon Williams (unspecified), Antony (knock), Anthony Martial (back), Jadon Sancho (illness)
Doubtful: None
Sports Mole's predicted XI: De Gea; Dalot, Martinez, Maguire, Shaw; Casemiro, Eriksen; Antony, Fernandes, Rashford; Ronaldo
For data analysis of the most likely results, scorelines and more for this match please click here.