Carlo Ancelotti's side are top of the table on 35 points, while Granada sit down in 19th position, having picked up just seven points this term, and here Sports Mole rounds up the team news for the two sides.
REAL MADRID vs. GRANADA
REAL MADRID
Out: Luka Modric (thigh), Vinicius Junior (thigh), Eduardo Camavinga (knee), Arda Guler (knee), Aurelien Tchouameni (foot), Eder Militao (knee), Thibaut Courtois (knee)
Doubtful: None
Sports Mole's predicted XI: Lunin; Vazquez, Nacho, Alaba, Mendy; Valverde, Kroos, Ceballos; Bellingham; Rodrygo, Joselu
GRANADA
Out: Jesus Vallejo (hamstring), Miguel Angel Rubio (ankle)
Doubtful: None
Sports Mole's predicted XI: Ferreira; R Sanchez, Torrente, Miquel, Neva; Villar, Gumbau, Melendo; Uzuni, Boye, Zaragoza
For data analysis of the most likely results, scorelines and more for this match please click here.