The Red Devils overcame Wolverhampton Wanderers 4-3 in Thursday's seven-goal spectacular, while the Irons came from behind to hold Bournemouth to a 1-1 draw, and here Sports Mole rounds up the team news for both clubs.
MANCHESTER UNITED vs. WEST HAM UNITED
MANCHESTER UNITED
Out: Anthony Martial (groin), Mason Mount (calf), Tyrell Malacia (knee)
Doubtful: Sofyan Amrabat (international), Aaron Wan-Bissaka (leg), Victor Lindelof (groin), Lisandro Martinez (foot)
Sports Mole's predicted XI: Onana; Dalot, Varane, Martinez, Shaw; Mainoo, McTominay; Antony, Fernandes, Rashford; Hojlund
WEST HAM UNITED
Out: Said Benrahma (suspended), Michail Antonio (knee), Lucas Paqueta (calf)
Doubtful: Nayef Aguerd (international)
Sports Mole's predicted XI: Areola; Coufal, Aguerd, Zouma, Emerson; Soucek, Alvarez; Kudus, Ward-Prowse, Cornet; Bowen
For data analysis of the most likely results, scorelines and more for this match please click here.