The Citizens beat Chelsea 2-0 to advance to the last-16 stage, while Jurgen Klopp's side needed penalties to get past Derby County, and here Sports Mole rounds up the team news for both clubs.
MANCHESTER CITY vs. LIVERPOOL
MANCHESTER CITY
Out: Julian Alvarez (international)
Doubtful: Kalvin Phillips, Jack Grealish, Kyle Walker, Phil Foden, John Stones, Aymeric Laporte, Rodri, Manuel Akanji, Ederson, Nathan Ake, Bernardo Silva, Joao Cancelo, Ruben Dias (all international)
Sports Mole's predicted XI: Ortega; Lewis, Katongo, Charles, S. Gomez; Palmer, Gundogan, De Bruyne; Mahrez, Haaland, Borges
LIVERPOOL
Out: Luis Diaz (knee), Arthur (thigh), Diogo Jota (calf), Ibrahima Konate (international), Curtis Jones (unspecified)
Doubtful: Virgil van Dijk, Alisson Becker, Fabinho, Trent Alexander-Arnold, Jordan Henderson (all international)
Sports Mole's predicted XI: Kelleher; Ramsay, J. Gomez, Phillips, Tsimikas; Elliott, Bajcetic, Oxlade-Chamberlain; Salah, Firmino, Carvalho
For data analysis of the most likely results, scorelines and more for this match please click here.