On current form, that looks unlikely after the Reds suffered a shock 2-1 defeat at home to Leeds United on Saturday, while Serie A leaders Napoli head to Merseyside on the back of an incredible 13-match winning streak in all competitions.
Here, Sports Mole rounds up the team news for both teams ahead of an intriguing clash.
LIVERPOOL vs. NAPOLI
LIVERPOOL
Out: Luis Diaz (knee), Arthur (thigh), Diogo Jota, Joel Matip (both calf), Naby Keita, Alex Oxlade-Chamberlain (both unregistered)
Doubtful: None
Sports Mole's predicted XI: Alisson; Milner, Konate, Van Dijk, Tsimikas; Elliott, Henderson, Jones; Salah, Firmino, Carvalho
NAPOLI
Out: Salvatore Sirigu (muscle), Amir Rrahmani (abductor)
Doubtful: None
Sports Mole's predicted XI: Meret; Di Lorenzo, Ostigard, Kim, Rui; Ndombele, Lobotka, Elmas; Lozano, Simeone, Raspadori
For data analysis of the most likely results, scorelines and more for this match please click here.