The 30-year-old is competing in his first major international tournament since suffering his cardiac arrest at Euro 2020, and he headlines an intimidating Denmark XI at the Education City Stadium.
Kasper Schmeichel unsurprisingly gets the nod in goal for the Danes, and he will be protected by a three-man defence of Joachim Andersen, Simon Kjaer and Andreas Christensen.
Rasmus Kristensen and Joakim Maehle will occupy the wing-back positions for Denmark, as Thomas Delaney and Pierre-Emile Hojbjerg take their spots in the engine room.
Eriksen's inclusion means that much-coveted playmaker Jesper Lindstrom must make do with a place on the bench, as Andreas Skov Olsen and Kasper Dolberg lead the line.
As for Tunisia, 24-goal Wahbi Khazri - the nation's second-highest goalscorer of all time - is only considered for a place on the bench alongside Manchester United's Hannibal Mejbri.
Denmark starting lineup: Schmeichel; Andersen, Kjaer, A. Christensen; Kristensen, Delaney, Hojbjerg, Maehle; Eriksen; Skov Olsen, Dolberg
Substitutes: Ronnow, Nelsson, Jensen, Braithwaite, Damsgaard, Norgaard, O. Christensen, Stryger Larsen, Wass, Wind, Poulsen, Cornelius, Skov, Lindstrom, Bah
Tunisia starting lineup: Dahmen; Talbi, Meriah, Bronn; Drager, Skhiri, Laidouni, Abdi; Ben Slimane, Msakni; Jebali
Substitutes: Ben Said, Mathlouthi, Hassen, Ifa, Ghandri, Mejbri, Khazri, Khenissi, Maaloul, Sassi, Romdhane, Chaalali, Jaziri, Kechrida, Sliti