Famalicao vs. Maritimo (Saturday, 3.30pm)
Seeking to make it three league wins on the bounce for the first time this season, Famalicao play host to Maritimo at the Estadio Municipal de Famalicao on Saturday.
O Maior das Ilhas, meanwhile, head into the weekend off the back of picking up three huge points in their battle at the bottom of the table and will look to build on that result.
We say: Famalicao 2-1 Maritimo
Following their performances at the weekend, Maritimo will head into the weekend with renewed belief as they look to salvage their season. However, Famalicao's campaign has taken a turn for the better in recent weeks and we are backing them to claim all three points and keep their race for a place in Europe alive.
Boavista vs. Rio Ave (Saturday, 6.00pm)
Boavista will be looking to make it two back-to-back home wins for the first time since September when they welcome Rio Ave to the Estadio do Bessa on Saturday.
Currently separated by just one point and one place in the Primeira Liga table, we anticipate a thrilling battle ensuing between the two sides as they push for a top-half finish.
We say: Boavista 1-1 Rio Ave
While Boavista and Rio Ave have run out of steam in recent weeks, they have an outside chance of securing a spot in Europe. With that said, both sides head into the weekend knowing defeat could effectively spell the end of their European ambitions. We predict they will take a cautious approach to the game and settle for a share of the spoils.
Pacos de Ferreira vs. Porto (Saturday, 8.30pm)
Pacos de Ferreira will be looking to pick up their first win in six weeks and resume their surge from the danger zone when they play host to Porto at the Estadio Capital do Movel on Saturday.
With Benfica dropping points at Chaves last weekend, Sergio Conceicao's side could potentially cut the lead at the top of the table to just one point with a win this weekend.
We say: Pacos de Ferreira 0-2 Porto
While Famalicao will be looking to kick-start their turnaround, they are no match for a Porto side who are currently firing on all cylinders. With Benfica's drop-off in form putting the Dragoes back in the title race, we are backing them to comfortably edge out the Pacenses and close the gap at the top of the table to just one point.