The Portugal captain had already got the crowd to shout 'Siuuu' as he celebrated scoring a penalty just over the hour mark in the World Cup group game between the two nations.
Advertisement
Andre Ayew then rose to level for Ghana, only for Fernandos Santos' side to score two more goals.
But after Ronaldo came off with his side firmly ahead, Ghana's Bukari pulled one back for his side as the clock edged towards full-time.
Advertisement
And the Ghana star clearly had one thing on his mind as he sent the ball into the back of the net.
As he ran towards the corner flag and cheekily let out Ronaldo's signature 'SIUUU'.
Cameras then panned to the former Manchester United player sat on the bench, who threw his hands in the air in frustration.
It was more in frustration at conceding as the game sprang into life in the second half after a dull first 45 minutes.
Advertisement
Advertisement
Ghana were desperate to get an equaliser and came so close in the final stages when Inaki Williams tried to pounce on a Diogo Costa error.
Advertisement
Hiding behind the Portugal goalkeeper, Williams waited for Costa to put the ball on the floor and when he did, he stole the ball for what seemed like a late equaliser, but slipped when it mattered.
Ghana now face tough clashes with South Korea and Uruguay in a bid to qualify for the knockout stages.
Sparta Rotterdam 
AZ Alkmaar 
Southampton 
Liverpool 
Como 
Fiorentina 
Sevilla 
Rayo Vallecano 
Ajax 
Pec Zwolle 
Palermo 
Sampdoria 
Ipswich 
Manchester Utd 
Napoli 
Roma 
Moreirense 
FC Porto 
Leganes 
Real Madrid 
Lazio 
Bologna 
Empoli 
Udinese 
CSKA Moscow 
Rubin 
Slovan Bratislava 
AC Milan 
Sparta Praha 
Atletico Madrid 
Valencia 
Barcelona 
Stade Brestois 29 
Bayer Leverkusen 
Red Bull Salzburg 
Bayern Munich 
Paris Saint Germain 
Inter 
RB Leipzig 
Manchester City 
Feyenoord 
Sporting CP 
Arsenal 
FC Rostov 
Spartak Moscow 
Aston Villa 
Juventus 
Celtic 
Club Brugge 
Dinamo Zagreb 
Borussia Dortmund 
Monaco 
Benfica 
PSV 
Shakhtar Donetsk 
Lokomotiv Moscow 
Dinamo Moscow