Similarly, the away side make the trip to Rotterdam aiming to pick up a third league win in as many matches and bounce back from their European disappointment in midweek.
Match preview
PSV were dumped out of the Champions League playoffs following a 1-0 second-leg defeat to Scottish side Rangers at the Philips Stadion on Wednesday.
Having played out a 2-2 draw in the first leg away from home, Ruud van Nistelrooy's were heavily fancied to get the job done on their own turf but Antonio Colak's opener on the hour mark was enough to send last season's beaten Europa League finalists through to Europe's premier club competition.
That was De Rood-witten's first defeat in nine matches across all competitions but it is, without a shadow of doubt, a highly consequential one nonetheless.
Coming up next for them is the challenge of an opposing side who have won just one of the previous 22 meetings between the sides, while also losing each of the most recent seven.
Still yet to taste defeat in any competitive match on the road since the turn of the year, Sunday's visitors will back themselves to get the job done away from home.
Newly-promoted Excelsior saw off the threat of Vitesse in a comfortable 3-1 victory when the teams went head to head two Fridays ago.
Two goals from Reda Kharchouch got Marinus Dijkhuizen's men off to a fine start and after Nikolai Baden Frederiksen pulled one back before half time, Kenzo Goudmijn put the game to bed in the second half.
Consequently, The Kralingers currently sit fourth in the Eredivisie table, three points behind league leaders Ajax having played a game fewer.
Unbeaten in seven straight games in front of their fans since early April, Sunday's hosts will be seeking to continue their fine form on home turf.
SBV Excelsior Eredivisie form:
SBV Excelsior form (all competitions):
PSV Eindhoven Eredivisie form:
PSV Eindhoven form (all competitions):
Team News
Excelsior's Nikolas Agrafiotis is expected to miss Friday's contest due to a muscle which has seen him miss seven matches on the bounce.
Twenty-eight-year-old Michael Chacon will also be unavailable for this weekend's hosts as he serves the third of a three-game suspension.
Olivier Boscagli remains ruled out with a long-term knee injury, and the Frenchman is not expected to play any part for PSV Eindhoven this weekend.
Carlos Vinicius and Noni Madueke are also ruled out through hamstring and ankle injuries respectively, while Mauro Junior is yet to fully recover from a groin problem.
Amid talks of a potential move to Manchester United, Cody Gakpo remains focused on his current employers and the forward is set to feature in this one.
SBV Excelsior possible starting lineup:
Van Gassel; Tjoe, El Yaakoubi, Nieuwpoort, Horemans; Azarkan, Baas, Eijgenraam, Goudmijn; Driouech, Kharchouch
PSV Eindhoven possible starting lineup:
Benitez; Max, Obispo, Ramalho, Teze; Gutierrez, Veerman, Sangare; Gakpo, De Jong, Saibari