The Imps will be looking to claim consecutive victories after ending a five-game winless run with a win over Cheltenham Town on Friday.
Match preview
Plymouth came from behind on Friday to secure a 3-1 away victory over Morecambe, which moved them to the top of the table.
Danny Mayor's 63rd-minute strike cancelled out Jensen Weir's opener, before Ben Waine gave Plymouth the lead in the 86th minute.
A Jay Matete strike in stoppage-time made rounded off a third consecutive victory, boosting the Pilgrim's hopes of securing promotion to the Championship, having spent the last 13 years in the bottom two tiers of the Football League.
Although third-placed Sheffield Wednesday have played a game more, Plymouth cannot afford to rest on their laurels with just two points separating them from the Owls.
Having won 17 of their 19 home league games this season, including their last three matches at Home Park, the Pilgrims will be confident that they can maintain their advantage at the League One summit on Monday.
Lincoln, meanwhile, picked up just two points from six matches prior to Saturday's home meeting with Cheltenham, but they managed to end their winless run with a 2-0 victory.
Ben House opened the scoring three minutes before half time, and the Lincoln striker added another in the 79th minute to wrap up all three points.
After finishing in 17th position last term, 14th-placed Lincoln will be looking to creep into the top half of the table before the curtain comes down on the 2022-23 campaign.
If the Imps are to pick up all three points on Monday then they will need to end a six-game winless away run, which has been made up of four draws and two defeats.
Lincoln can draw inspiration from the fact that they emerged victorious in their most recent trip to Home Park, claiming a 2-1 victory in January 2022.
Plymouth Argyle League One form:
W
W
L
W
W
W
Plymouth Argyle form (all competitions):
W
L
W
W
L
W
Lincoln City League One form:
D
L
L
L
D
W
Team News
The hosts are expected to be without the services of James Bolton and Adam Randell due to hamstring and ankle injuries respectively.
Mayor dropped out of the lineup against Morecambe, but after coming off the bench to score Plymouth's first goal, he could be recalled to the starting XI
Waine could also be rewarded with a place in the side for finding the net on Friday, which could result in Sam Cosgrove dropping down to the bench.
As for the visitors, they recently confirmed that defender Lewis Montsma will miss the rest of the season with a knee injury.
TJ Eyoma, who has been sidelined since February, is closing in on a return and there is a possibility that he could feature among the substitutes.
After ending their winless run on Friday, Lincoln boss Mark Kennedy could be tempted to name an unchanged starting XI.
Plymouth Argyle possible starting lineup:
Burton; Wilson, Scarr, Galloway; Edwards, Houghton, Butcher, Miller; Mayor; Waine, Hardie
Lincoln City possible starting lineup:
Rushworth; O'Connor, Jackson, Poole; Soresen, Erhahon, Sanders, Boyes; Bishop, Mandriou; House