Drawn in Group C of the qualifying campaign, the teams are joined by Cameroon and Kenya in the battle to book a place in Ivory Coast next year.
Match preview
Off the back of a 1-0 defeat versus Togo in their final involvement of 2021, Namibia will take to the field for the first time since the turn of the year.
Meme Placca's strike in the dying embers of the aforementioned game was enough to decide a dead rubber World Cup qualifying contest in Johannesburg
Consequently, Bobby Samaria's men have now been beaten for the third time in four matches and still boast just one win from their last eight outings.
The Brave Warriors are in need of a pick-me-up as they kick off their quest to reach the AFCON finals for the first time since the 2019 edition in Egypt.
Standing in the way is an opposing outfit with little to choose between the sides are the previous two meetings have yielded 3-1 victories for either team.
Burundi claimed a 2-1 victory over the Lone Stars of Liberia in their most recent fixture which was a friendly on March 29 at the Mardan Sports Complex.
A first-half brace from Bonfils-Caleb Bimenyimana put Jimmy Ndayizeye's men in the driving seat before Divine Teah halved the deficit in the early exchanges of the second period.
Les Hirondelles have now snapped a run of five games without a win and will be looking to pick up where they left off during the last international break.
Still in search of their maiden appearance at Africa's biggest football showpiece, Saturday's visitors set out to kick off their qualification journey on a positive note.
Namibia form (all competitions):
Burundi form (all competitions):
Team News
Petrus Shitembi is back in action for Namibia after the midfielder spent a lengthy spell on the sidelines due to a knee injury.
Peter Shalulile has scored each of his nation's last two goals and the 28-year-old is definitely one to look out for this weekend.
Meanwhile, Tiberius Lombard and Manfred Starke will not play any part for the hosts as they are both unavailable due to personal reasons.
Off the back of a brace in his last international outing, Bonfils-Caleb Bimenyimana will be looking to deliver the goods once again.
Youssouf Ndayishimiye has not featured in any game since late March and the 23-year-old remains out of contention for Burundi.
Namibia possible starting lineup:
Kazapua; Nyambe, Haoseb, Hambira, Gebhardt; Handura, Shitembi, Papama; Shalulile, Kambindu, Kamatuka
Burundi possible starting lineup:
Nahimana; Nihorimbere, Moussa, Ndizeye, Ramazani; Nduwarugira, Bigirimana, Nzigamasabo; Amissi, Bimenyimana, Liongola