The visitors, meanwhile, have failed to score in their last two league outings and are winless in their last eight matches across all competitions.
Match preview
Accrington Stanley's FA Cup fairytale came to a halt last time out, after John Coleman's side were defeated 3-1 by Leeds United in an entertaining fifth-round tie.
Jack Harrison scored a stunning 25-yard drive, after Patrick Bamford's effort broke the deadlock halfway through the first half.
Bamford completed his brace in the second half to secure Leeds' place in the next round, although 18-year-old substitute Leslie Adekoya scored a consolation for Stanley with his first senior goal 38 seconds after coming off the bench.
Now, Accrington's attention turns to league matters, where they currently sit in 21st place due to goal difference, level on points with MK Dons. However, they have played three games less than the Dons, and should results go their way, they could move out of the relegation zone if they manage to pick up a positive result on Saturday.
Coleman's side are seeking to make it back-to-back league wins at home, after dispatching Bristol Rovers last time out, courtesy of strikes from Tommy Leigh and Ryan Astley.
Meanwhile, Lincoln City's winless run continued with a goalless draw against a struggling Cambridge United side.
The Imps have now gone eight games without a victory in League One, a worrying run which stretches back to mid-November.
This winless run has left Mark Kennedy's side lingering six points above the relegation zone, and in 16th place in the League One table.
It has been a goalscoring threat that the visitors have lacked this season, scoring only 24 goals in the league - only two teams have scored fewer this season.
Lincoln have drawn 13 games this season, which is the highest in the division, and Kennedy will know that his side need to turn some of those draws into victories if they are to start moving higher up the table.
Accrington Stanley League One form:
D
D
L
L
W
L
Accrington Stanley form (all competitions):
D
W
W
L
W
L
Lincoln City League One form:
L
D
D
L
D
D
Lincoln City form (all competitions):
D
D
L
L
D
D
Team News
Accrington trio Joe Pritchard, Jay Rich-Baghuelou and David Morgan are ruled out for the rest of the season due to injury, while Matt Lowe is set to remain sidelined for the next six weeks.
Nathan Butler-Oyedeji joined the Reds from Arsenal on loan until the end of the season on transfer deadline day, so he could make his debut this weekend.
As for the visitors, Ethan Erhahon, Dylan Duffy and Luke Plange all joined the Imps on deadline day so all three could be involved in the starting XI this weekend.
Jack Diamond is the club's top scorer in League One this term with eight goals, so it is expected that he will retain his place in Lincoln's attack on Saturday.
Accrington Stanley possible starting lineup:
Savin; Rodgers, Astley, Tharme; Longelo, Martin, Coyle, Hamilton, McConville; Pressley, Leigh
Lincoln City possible starting lineup:
Rushworth; Poole, O'Connor, Jackson, Roughan; Bishop, Sanders, Mandroiu; Vernam, Plange, Diamond
We say: Accrington Stanley 1-1 Lincoln City
Accrington Stanley's home record does not make for great reading, but Lincoln's poor run of results makes us think that John Coleman's side can claim at least a point here.