The Scottish side were able to return from Azerbaijan with a 1-0 defeat, giving Stephen Glass's squad a realistic chance of making further progress in the competition.
Match preview
Despite the prospect of a long trip to Azerbaijan last week, Stephen Glass would have had total confidence that his players could return to Scotland still in this tie.
That is exactly what transpired with the Dons limiting their hosts to a 30th-minute goal on a pitch which was condemned by Glass after the full-time whistle.
While the injury to Andrew Considine is a considerable blow, the result itself means that Aberdeen can look to use their home advantage to claim their biggest European victory since 2007.
Going three games without success is not ideal preparation for this encounter, but positives could be taken from Sunday's 1-1 draw at Hearts.
Glass will want to see more from summer arrival Christian Ramirez, who has now gone five matches without finding the back of the net.
Qarabag are no strangers to qualifying for European competition and having to fight hard to feature in the Europa Conference League group stages will feel like somewhat of a comedown.
Nevertheless, Gurban Gurbanov is motivated to respond to a 2020-21 campaign which promised so much, Qarabag losing the league title on the last day of the season and exiting two cup competitions via penalty shootouts.
To their credit, they have come through their opening seven fixtures without suffering defeat, but Sunday's win over Sabail was the first time that they have scored more than one goal in a game.
Nineteen-year-old Musa Qurbanli netted twice during a 3-0 win, producing a performance which suggested that he is ready to take on more responsibility in the first team.
Aberdeen Europa Conference League form:
Aberdeen form (all competitions):
Qarabag FK Europa Conference League form:
Qarabag FK form (all competitions):
Team News
Glass is expected to be forced into at least one change with Connor McLennan being substituted before the break at Hearts.
Jay Emmanuel-Thomas appears most likely to be brought into the Aberdeen starting lineup, but Ryan Hedges and Considine remain on the sidelines.
Jonny Hayes only lasted 45 minutes at the weekend, and his absence would lead to a further rethink for Glass.
Barring any late issues, Gurbanov will see little reason to make any alterations to the team which started the first leg.
Taking that approach would result in Qurbanli dropping back down to the substitutes' bench.
Aberdeen possible starting lineup:
Lewis; Ramsay, Gallagher, McCrorie, Hayes; Brown, Ferguson; Ojo, Jenks, Emmanuel-Thomas; Ramirez
Qarabag FK possible starting lineup:
Mahammadaliyev; Huseynov, Medina, Medvedev, Bayramov, Zoubir, Romero, Malinowski, Andrade, Qarayev, Sheydayev
We say: Aberdeen 1-1 Qarabag FK
Regardless of how this match pans out on Thursday evening, we do not expect many goals. Aberdeen will want to attack from the off in a bid to make a statement, but Qarabag's greater experience in European competition could prove crucial as the game progresses.