Hellas Verona vs. Napoli (Monday, 5.30pm)
Napoli begin their season with a fixture against Hellas Verona looking to make a positive start after the disappointment of missing out on the Serie A title last season.
Meanwhile, it has been a summer of change at Stadio Marcantonio Bentegodi with Gabriele Cioffi being brought in as the replacement for Igor Tudor, who was handed an opportunity at Marseille.
We say: Hellas Verona 1-2 Napoli
With some influential names missing from this Napoli squad, they are heading somewhat into the unknown this season. However, with Verona under new leadership, we feel that the visitors should have enough quality to edge what should prove to be a tight contest.
Juventus vs. Sassuolo (Monday, 7.45pm)
After an uncharacteristic period of struggle, Juventus aim to get back on track in 2022-23, and they kick off their campaign by hosting Sassuolo on Monday.
While the Bianconeri finished fourth for the second straight season, their visitors slipped to 11th despite some typically enterprising displays - including a 2-1 win over Juve in October.
We say: Juventus 1-1 Sassuolo
Due to an upheaval in personnel - plus a series of injuries and suspensions - Juve may struggle to settle in to the new Serie A season at the first attempt, and it would be no surprise if they fail to take three points.
Sassuolo regularly recover from losing their best players - including Manuel Locatelli to their hosts - so remain good value for a first-day draw.