The forward needed to be withdrawn prior to extra time commencing against Real Madrid in the second leg of their Champions League quarter-final tie on Wednesday night.
That issue has subsequently led to the Norway international being left out of the squad, but Kevin De Bruyne - who also requested to be substituted before the conclusion of extra time - is named in the starting lineup.
Manchester City: Ortega; Walker, Stones, Akanji, Ake; Rodri, De Bruyne, Bernardo, Foden, Grealish; Alvarez
Subs: Ederson, Dias, Kovacic, Doku, Gomez, Gvardiol, Nunes, Bobb, Lewis
Chelsea: Petrovic; Gusto, Chalobah, Silva, Cucurella; Caicedo, Fernandez, Gallagher; Madueke, Palmer, Jackson
Subs: Bettinelli, Badiashile, Disasi, Gilchrist, Chilwell, Chukwuemeka, Mudryk, Sterling, Washington
More to follow.