The 26-year-old broke into the Red Devils squad while Van Gaal was in charge during the 2015/16 season.
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In total, the defender made 14 appearances across all competitions after being promoted to the first-team following an injury crisis.
After making his debut against West Brom in November 2015, Van Gaal said: "I have seen him once or twice and I have been impressed by him.
"I knew that Marouane Fellaini was injured, so I talked with Warren Joyce and asked what he had for me.
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"I'm always talking with him or Paul McGuinness, and he said at the moment the left full-back is in good shape.
"I needed a left full-back because Marcos Rojo had played a few games in a row, so I have to take into account that it might be too much.
"I put Cameron in the line-up without any fear, and I have to say he did very well."
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Fast-forward nearly eight years and Borthwick-Jackson has just been released by Burton after two years at the club.
The left-back had played 72 times for the Brewers before his release was announced by the club - the most he has appeared for any side in his career.
But he is now on the lookout for a new team with his contract to come to an end in the summer.
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He had helped Burton to finish 15th in the table - an improvement on the 16th they ended up in last campaign.
However, his performances did not warrant a contract extension and Borthwick-Jackson is now on the hunt for his fourth professional team.
The Manchester-born defender made several loan moves following his breakout campaign under Van Gaal, where he was shipped off to Wolves, Leeds, Scunthorpe, Tranmere and Oldham.
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He eventually joined the latter on a permanent transfer in 2020 after being released by United, though he spent just one year at Boundary Park after they decided against giving him a new deal.