The victors of this two-legged contest will face either Molde FK or Silkeborg IF in the third qualifying round.
Match preview
After finishing 10th and six points above the relegation zone in the 2022-23 Scottish Premiership campaign, Kilmarnock went from strength to strength under Derek McInnes last season, securing a fourth-placed finish and a Europa League qualification spot.
McInnes, who has completely revitalised Killie's fortunes since taking the reins in January 2022, was subsequently named Manager of the Season and has since extended his contract at the club until the summer of 2027.
Spirits are understandably high within the Kilmarnock camp and it is fair to say that they have found their shooting boots in pre-season, following up a 4-0 victory over Auchinleck Talbot with a thumping 5-0 success at home to Barrow last Friday; they also claimed a five-goal win over The New Saints at the beginning of this month.
Kilmarnock have one final friendly fixture against Annan Athletic sandwiched between their two-legged Europa League clash with Cercle Brugge, before they begin the 2024-25 Scottish Premiership away against champions Celtic on August 4.
Like Kilmarnock, Cercle Brugge are competing in the Europa League qualifiers for just the second time in their history after finishing fourth in the Belgian Pro League Champions' Playoffs last season.
Despite winning only three of their final 10 league games, Groen en Zwart pipped Genk to fourth place, finishing above them on goal difference to claim the last remaining Europa League qualification spot.
Miron Muslic's side have since taken part in three friendly fixtures in preparation for the new season, beginning with a 3-2 win over AEK Larnaca before playing out a 1-1 draw with Monaco on July 13.
Cercle Brugge were then condemned to a slender 1-0 defeat to Feyenoord in an intensive 120-minute-long friendly last Saturday, but it was nevertheless a good and instructive practice game from which Muslic will have taken positives ahead of their first competitive match of the new season on Thursday.
Kilmarnock form (all competitions):
Cercle Brugge form (all competitions):
Team News
Kilmarnock have made just two signings so far this summer, recruiting forward Bruce Anderson and goalkeeper Robby McCrorie who have both taken part in pre-season and are in contention to start on Thursday.
Marley Watkins, last season's top scorer with 13 goals, could form a partnership in attack with either Anderson or Kyle Vassell, while key men including Stuart Findlay, David Watson and Danny Armstrong are set to be included in a strong first XI.
As for Cercle Brugge, new signing Ibrahim Diakite is set to make his first competitive appearance at right-back, potentially joining Jesper Daland, Boris Popovic and Nazinho in a four-man defence.
Kevin Denkey scored an impressive 28 goals in all competitions for the Belgian outfit last season and he is expected to lead the line against Kilmarnock, joining Alan Minda, Felix Lemarechal and Yann Gboho in attack.
Kilmarnock possible starting lineup:
McCrorie; Mayo, Deas, Findlay, Ndaba; Armstrong, Donnelly, Watson, Kennedy; Anderson, Watkins
Cercle Brugge possible starting lineup:
Warleson; Diakhite, Daland, Popovic, Nazinho; Lopes, Van Der Bruggen; Somers, Goncalves, Lemarechal, Augusto; Denkey
We say: Kilmarnock 1-1 Cercle Brugge
Both teams will fancy their chances of coming out on top in this first-leg tie, particularly Kilmarnock on home soil, but we expect a somewhat cagey affair to take place on Thursday which could lead to a share of the spoils, keeping the tie finely poised ahead of the reverse fixture next week.