The Foxes have been in poor form since the season restarted and are now desperate for a win to help turn around their fortunes.
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Brendan Rodgers' side won the FA Cup two years ago and they will be hoping to pull off another impressive cup run to bring some positivity to their campaign.
Opponents Gillingham have also had a torrid time in the fourth tier, sitting at the bottom of the table and without a win in 13 games.
With both sides struggling in their respective leagues, a win for either team would provide a huge boost to their season.
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Gillingham vs Leicester: talkSPORT coverage
This FA Cup Third Round tie will be played on Saturday, February 7.
Kick off at Priestfield Stadium is scheduled for 12:30pm.
talkSPORT 2 will have live coverage of the game with commentary provided by Ian Danter and former Chelsea defender Scott Minto.
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To tune in to talkSPORT or talkSPORT 2 through the website, click HERE for the live stream.
You can also listen via the talkSPORT app, on DAB digital radio, through your smart speaker and on 1089 or 1053 AM.
Gillingham vs Leicester: Team news
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Gillingham will be without Elkan Baggott who has been ruled out with an ankle issue but the remainder of the squad is fit.
As for Leicester, they have a long injury list to contend with after losing both Boubakary Soumare and Kiernan Dewsbury-Hall against Fulham.
The midfielders joined James Maddison, Patson Daka, Jonny Evans, Dennis Praet, Ricardo Pereira and James Justin on the sidelines.
Gillingham vs Leicester: What has been said?
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Leicester forward Ayoze Perez is hopeful that the clash with Gillingham will help start to turn things around for the Foxes.
"It's a good test for us going away from home," he said.
"It's a great game to build confidence as well, we want to get back to a winning feeling. Going out there and getting the win would help us in many ways. Hopefully, we can start building out from there.
"When you're in a negative run, the good thing is that when you've got many games in a row, you can straight away turn things around, so after Tuesday we've got another game on Saturday, that comes really quick so that's great.
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"It's another chance to turn things around."
Gillingham vs Leicester: Match facts
Since his first appearance in the competition in January 2016, Leicester's Kelechi Iheanacho has scored more FA Cup goals than any other player (15). 13 of these goals have come in his 14 starts in the competition.
Leicester have progressed from their FA Cup third round tie in five of the last six seasons, failing only against fourth-tier Newport County in 2018-19 in this run.
Gillingham have been knocked out in five of their last six FA Cup third round ties, although the one exception came against Premier League opposition in 2018-19 when they beat Cardiff City 1-0. The Gills have never reached the fourth round when playing in the fourth tier of English football.
The only previous occasion Leicester have faced Gillingham in a cup competition was in the fourth round of the 1963-64 League Cup, a 4-1 win for the Foxes who went on to lift the trophy that season.
This is the first meeting between Gillingham and Leicester in the FA Cup and first in any competition since the 2004-05 Championship campaign, with the Foxes winning both games 2-0. Matt Heath and Dion Dublin scored their goals in the victory at the Priestfield.
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