Accrington vs. Port Vale (Friday, 3.00pm)
Accrington Stanley will attempt to end a six-game winless run when they welcome Port Vale to the Wham Stadium for Friday's League One contest.
Like their hosts, the Valiants are also enduring a poor run of form after failing to win any of their last four matches.
We say: Accrington Stanley 1-1 Port Vale
Accrington and Port Vale played out a 1-1 draw when they met in February, and with both sides struggling for victories, we think that Friday's fixture will also finish all square.
Bristol Rovers vs. Charlton (Friday, 3.00pm)
Charlton Athletic will attempt to extend their unbeaten run to six matches when they travel to the Memorial Stadium to face Bristol Rovers on Friday.
The Addicks, who are currently sitting in 12th place in the League One table, are seven points better off than their hosts, who have lost their last two matches.
We say: Bristol Rovers 0-2 Charlton Athletic
Charlton will carry significant momentum into Friday's encounter after extending their unbeaten run to six matches with a resounding 6-0 win over Shrewsbury, and we think that they will continue their fine form by brushing aside a Bristol Rovers team that have failed to win any of their last seven competitive home games.
Burton Albion vs. Barnsley (Friday, 3.00pm)
Barnsley will continue their promotion push when they travel to the Pirelli Stadium to face Burton Albion in Friday's League One contest.
The Tykes have won five of their last six matches, while the Brewers have picked up four points from their last two fixtures.
We say: Burton Albion 1-3 Barnsley
Barnsley claimed a 2-0 victory when they faced Burton at Oakwell in December, and although they do not have home advantage on this occasion, we think that they have enough quality in their squad to complete a league double over the Brewers.
Cambridge vs. Fleetwood (Friday, 3.00pm)
Cambridge United's battle to escape the League One relegation zone will continue on Friday afternoon when they welcome Fleetwood Town to Cambridgeshire.
The home side are currently 23rd in the table, five points from the safety of 20th position, while Fleetwood occupy 13th, boasting 50 points from their 39 league games this term.
We say: Cambridge United 1-1 Fleetwood Town
Two of the last three meetings between these two sides have finished in draws, and we are predicting another stalemate on Friday afternoon. Cambridge were excellent against Port Vale last time out and will fancy their chances of avoiding defeat in front of their own supporters here.
Exeter vs. Bolton (Friday, 3.00pm)
Bolton Wanderers will be bidding to continue their League One promotion charge when they make the trip to Devon on Friday afternoon to face Exeter City.
The visitors are currently fifth in the table, level on points with seventh-placed Derby County, while Exeter occupy 11th position, 11 points behind their opponents in this contest.
We say: Exeter City 1-1 Bolton Wanderers
Exeter's recent home form has been excellent, and this has the potential to be a very tough game for Bolton, who are not in the best of form in the league. It would not be a shock to see a home or indeed an away win, but we just have a feeling that the points will be shared in Devon.
Forest Green vs. Derby (Friday, 3.00pm)
Derby County will be bidding to end a three-game losing run in League One when they travel to bottom-of-the-table Forest Green Rovers on Friday afternoon.
The Rams will enter the contest off the back of a 2-0 home defeat to Ipswich Town, while Forest Green suffered a 1-0 loss at Portsmouth in their last fixture in the third tier of English football.
We say: Forest Green Rovers 0-1 Derby County
This is a huge match for both sides, and it is set to be a fascinating battle on Friday afternoon. Derby desperately need a win to put to an end their recent poor run, and we are tipping the Rams to navigate their way to a huge three points in this contest.
Ipswich vs. Wycombe (Friday, 3.00pm)
Promotion-chasing Ipswich Town will go in search of an eighth successive victory when Wycombe Wanderers visit Portman Road on Friday afternoon.
The Tractor Boys sit two points outside of the automatic promotion places in League One, while the Chairboys find themselves eighth - 16 points shy of Ipswich.
We say: Ipswich Town 2-0 Wycombe Wanderers
We expect Ipswich Town to extend their run of clean-sheet wins to eight matches with a comfortable victory over Wycombe Wanderers, whose struggles look set to continue following the departure of Ainsworth.
Lincoln vs. Cheltenham (Friday, 3.00pm)
Lincoln City will be aiming to end a winless run of five matches when they host Cheltenham Town on Good Friday.
Cheltenham, meanwhile, have put together an unbeaten run of six games to move away from relegation danger.
We say: Lincoln City 1-1 Cheltenham Town
With both teams almost completely safe from any lingering fears of relegation, we expect this to be a slightly more entertaining match than the goalless stalemate played out in Gloucestershire last month.
However, both managers are keen to build on a strong defence, hence why these sides have averaged scoring fewer than one goal per game across the course of the game. We can envisage a low-scoring draw.
MK Dons vs. Portsmouth (Friday, 3.00pm)
Two sides that are unbeaten in four matches will face off when MK Dons welcome Portsmouth to Stadium MK on Friday.
The hosts are currently sitting in 19th position in the League One table, while the visitors are in ninth place.
We say: MK Dons 1-2 Portsmouth
Both teams will head into Friday's encounter in a confident mood, but we think playoff-chasing Pompey will have the extra quality needed to claim a narrow victory.
Morecambe vs. Plymouth (Friday, 3.00pm)
Having suffered a humbling 4-0 defeat to Bolton Wanderers in last weekend's EFL Trophy final, Plymouth Argyle will resume their promotion push when they return to League One action on Friday.
Sitting second in the table on goal difference, the Pilgrims will make the long trip to Lancashire to face relegation-threatened Morecambe, who find themselves four points inside the drop zone.
We say: Morecambe 1-3 Plymouth Argyle
We can see Plymouth Argyle producing a big response after last weekend's Wembley humiliation, with the visitors expected to enhance their promotion prospects while piling more pressure on lowly Morecambe.
Oxford Utd vs. Sheff Weds (Friday, 3.00pm)
Oxford United host Sheffield Wednesday on Good Friday in what could potentially prove to be a pivotal clash at both ends of League One's table.
Sheff Wed head into the bank holiday weekend's action top of the table on goal difference, while Oxford are only one position and three points above the relegation zone.
We say: Oxford United 1-2 Sheffield Wednesday
Despite there being 19 places and 42 points between these two sides heading into Friday's encounter, Oxford have shown signs of trending in the right direction under Manning's stewardship in their last two matches.
However, Sheffield Wednesday's winless run surely cannot continue much longer, and we expect them to claim a tight victory to remain top of the table.
Shrewsbury vs. Peterborough (Friday, 3.00pm)
Peterborough United will be looking to consolidate their place in the League One playoffs when they travel to Montgomery Waters Meadow to take on Shrewsbury Town on Friday afternoon.
The visitors are sixth in the table, currently occupying the last available playoff position, while the hosts are in 10th place.
We say: Shrewsbury Town 1-1 Peterborough United
Peterborough have a terrible recent record away at Shrewsbury, and they struggled to create much of anything last time out against Oxford, so we expect them to draw for the second game on the spin.
The Shrews will be looking to bounce back from a very disappointing 6-0 defeat against Charlton last weekend, and for the most part they have been a much better side at home, going unbeaten at Montgomery Waters Meadow since New Year's Day.