Salah went into Egypt's second group game in a confident mood after registering a goal and an assist in his country's tournament opener against Mozambique.
Unfortunately for the 31-year-old, he was unable to make it until half time after picking up an injury issue in the closing stages of the first period.
The Egypt captain dropped to the ground with a suspected hamstring problem, before he was replaced in first-half stoppage time by Mostafa Fathi.
Despite being without their talisman, Egypt showed great character to fight back from behind on two occasions to draw 2-2 with Ghana.
Eintracht Frankfurt's Omar Marmoush and Nantes' Mostafa Mohamed both grabbed a goal apiece to cancel out a brace for West Ham United's Mohamed Kudus.
Speaking in his post-match press conference, Vitoria attempted to play down any serious concerns over Salah's injury.
"I hope it's not a big problem," Vitoria told reporters. "But it was a problem in the first half, because we lost one time to make a substitution. In the second half we only had two moments to make substitutions."
Vitoria went on to add: "Now I don't know because it's [too] early to see something. I think it's not dangerous, but let's see if Salah recovers."
The Egypt coach will hope to have Salah available for the country's final group game against Cape Verde on Monday when they will attempt to book their place in the knockout rounds.
Having drawn their opening two games, the Pharaohs are currently sitting in second place and one point behind Group B leaders Cape Verde, who will face Mozambique in their second game on Friday.
While Egypt will want Salah to make a quick recovery, Liverpool will also be keen to establish the severity of his injury.
Salah has continued to be a key player for Jurgen Klopp's side this season, having registered 18 goals and provided nine assists in 27 competitive appearances.