The Blues suffered their first defeat of the season on Saturday afternoon, with Manchester City recording a 1-0 victory at Stamford Bridge in the Premier League.
Thomas Tuchel's side will be aiming to move onto six points in Group H, having opened their section with a 1-0 home success over Zenit St Petersburg on September 14.
Here, Sports Mole rounds up all of Chelsea's latest injury and suspension news ahead of the contest with Juventus, who beat Malmo 3-0 in their Group H opener.
Christian Pulisic
Status: Major doubt
Type of injury: Ankle
Possible return date: September 29 (vs. Juventus)
Chelsea were again without the services of Christian Pulisic on Saturday due to an ankle problem that the attacker picked up while representing the United States over the international break, and he remains a doubt for this contest.
Reece James
Status: Out
Type of injury: Ankle
Possible return date: Unknown
Reece James twisted his ankle during Saturday's defeat to Man City, and it is highly unlikely that the England international will be available for selection until after the international break.
Mason Mount
Status: Minor doubt
Type of injury: Knock
Possible return date: September 29 (vs. Juventus)
Mason Mount was ruled out of the Man City clash due to a knock that he suffered against Villa in the EFL Cup, but the England international has a strong chance of returning for this match.
CHELSEA'S SUSPENSION LIST
Chelsea have no players suspended for the Champions League contest.