Spurs moved quickly to appoint the Italian on Tuesday - just a day after Nuno Espirito Santo was sacked following a run of three defeats in four games.
One of those losses saw the Lilywhites go down 1-0 to Dutch outfit Vitesse to leave them third in Group G on just four points.
Conte will want to get his tenure off to a winning start at home.
Tottenham vs Vitesse: Date and kick-off time
The Europa Conference League clash is set to take place on Thursday, November 4 at the Tottenham Hotspurs Stadium in London.
Kick-off is set for 8pm UK time.
Spurs next travel to Slovenia to take on Mura before finishing their group-stage journey at home to Ligue 1 outfit Rennes.
Tottenham vs Vitesse: TV channel and live stream
The Group G clash will be live on BT Sport ESPN with coverage starting at 7:30pm.
BT Sport subscribers can live stream this match via the app on their computer, mobile and tablet devices.
Tottenham vs Vitesse: Team news
Conte is expected to deploy his effective 3-5-2 system at Spurs should his work permit be granted in time for the Italian to take to the dug-out.
The likes of Matt Doherty and Dele Alli will be vying for midweek opportunities under the ex-Chelsea chief, with Harry Kane set to lead the line.
But both Bryan Gil and Ryan Sessegnon are set to miss out due to their respective hamstring injuries.
As for Vitesse, Wittek, who scored the winner against Spurs the last time they met, sustained an injury during that contest and is not fit to travel.
Million Manhoef is also a doubt with a knee issue but Matus Bero is back from a domestic suspension this week.
Tottenham vs Vitesse: What has been said?
Conte vowed to deliver attractive football upon his arrival at the club.
"To be Tottenham manager is a great pleasure, a great honour," He said.
"Now I want to repay this trust. My coaching philosophy is very simple: to play good football and attractive football for our fans with passion. To have a stable team, not up and down.
"The fans deserve to have a competitive team with a will to fight. I'll do everything to deserve their support.
"Tottenham is an important club in England and around the world. The stadium and training ground are wonderful. The club and Daniel Levy wanted me strongly. This is a good opportunity, an honour to accept and become the manager.
"I have seen on Tuesday the training ground and I want to start work. I arrive at a top club. These situations push you and increase the desire to do something important for the fans of this club."
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