The Reds currently top the standings with a one-point lead over the visitors and two-point advantage over Arsenal, who will rise to the summit if they beat Brentford on Saturday, and here Sports Mole rounds up the team news for both clubs.
LIVERPOOL vs. MANCHESTER CITY
LIVERPOOL
Out: Ben Doak (knee), Joel Matip (knee), Trent Alexander-Arnold (knee), Alisson Becker (thigh), Stefan Bajcetic (calf), Thiago Alcantara (muscle), Curtis Jones (shin), Ryan Gravenberch (ankle)
Doubtful: Ibrahima Konate (hamstring), Jayden Danns (concussion)
Sports Mole's predicted XI: Kelleher; Bradley, Gomez, Van Dijk, Robertson; Szoboszlai, Endo, Mac Allister; Salah, Nunez, Diaz
MANCHESTER CITY
Out: Jack Grealish (groin)
Doubtful: Jeremy Doku (muscle), Matheus Nunes (finger)
Sports Mole's predicted XI: Ederson; Walker, Dias, Stones, Ake; Silva, Rodri, De Bruyne; Foden, Haaland, Alvarez
For data analysis of the most likely results, scorelines and more for this match please click here.