The Lilywhites blew the race for Champions League football wide open with a 4-0 thrashing of Aston Villa at the weekend, where Son Heung-min, Timo Werner, Brennan Johnson and James Maddison made the net bulge.
Ange Postecoglou's men still reside in fifth place in the table, but they now only have a two-point gap to make up to the Lions, who have played a game more.
Here, Sports Mole rounds up Tottenham's latest injury and suspension news ahead of the clash with Fulham, who fell to a 2-1 loss versus Wolverhampton Wanderers in gameweek 28.
Micky van de Ven
Status: Out
Type of injury: Knee
Possible return date: March 30 (vs. Luton Town)
Early into the second half of the win over Villa, Dutch defender Micky van de Ven succumbed to a knee injury and had to be replaced by Radu Dragusin. The seriousness of his issue has not been disclosed, and while he is expected to miss Saturday's game, there is reportedly hope that he will return following the international break.
Richarlison
Status: Out
Type of injury: Knee
Possible return date: Unknown
Despite telling Brazilian media that he was on track to return from his own knee issue at Villa Park, Richarlison's comments were premature, and the attacker is not expected to recover in time for the derby with Fulham either.
Fraser Forster
Status: Out
Type of injury: Foot
Possible return date: Unknown
Second-choice goalkeeper Fraser Forster sustained a fracture in his foot last month, and the England international is unlikely to be back to full fitness until the latter stages of April.
Manor Solomon
Status: Out
Type of injury: Knee
Possible return date: Unknown
Israeli winger Manor Solomon is on the mend from a second knee operation, and no timeframe has been placed on his recovery, but he should be back on the field in the not-so-distant future.
Ryan Sessegnon
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
In contrast, the hapless Ryan Sessegnon is expected to miss the remainder of the season owing to the hamstring injury he sustained on Under-21s duty in February, which required an operation.
TOTTENHAM HOTSPUR'S SUSPENSION LIST
Tottenham have no players suspended for this match.