While the Red Devils suffered a 3-1 defeat at Arsenal before the international break, the Seagulls beat Newcastle United by the same scoreline last time out, and here, Sports Mole rounds up all of the latest team news for the two clubs.
MANCHESTER UNITED vs. BRIGHTON & HOVE ALBION
MANCHESTER UNITED
Out: Raphael Varane (muscle), Luke Shaw (muscle), Tyrell Malacia (muscle), Tom Heaton (calf), Amad Diallo (knee), Kobbie Mainoo (ankle), Antony (leave of absence)
Doubtful: Lisandro Martinez (foot), Sofyan Amrabat (back), Mason Mount (thigh), Jadon Sancho (other)
Sports Mole's predicted XI: Onana; Wan-Bissaka, Lindelof, Martinez, Dalot; Casemiro, Eriksen; Garnacho, Fernandes, Rashford; Hojlund
BRIGHTON & HOVE ALBION
Out: Julio Enciso (knee), Jakub Moder (knee)
Doubtful: Evan Ferguson (knee), Danny Welbeck (unspecified)
Sports Mole's predicted XI: Verbruggen; Milner, Webster, Dunk, Estupinan; Gross, Gilmour; March, Fati, Mitoma, Pedro
For data analysis of the most likely results, scorelines and more for this match please click here.