Carlo Ancelotti's side opened up an 11-point advantage at the summit by beating second-placed Barcelona in El Clasico on Sunday evening, with the capital side now in a commanding position in the division.
Los Blancos will tackle Real Sociedad on Friday before heading to Bayern Munich next week for the first leg of their Champions League semi-final.
Here, Sports Mole rounds up Real Madrid's injury and suspension news ahead of their clash with Real Sociedad, who currently occupy sixth spot in Spain's top flight.
Thibaut Courtois
Status: Out
Type of injury: Knee
Possible return date: Unknown
Courtois underwent surgery on an ACL injury last August; the Belgian had been in line to return at the end of March, but it was revealed before the last international break that he had suffered another knee injury, and he is unlikely to play again this term despite making a recent return to training.
David Alaba
Status: Out
Type of injury: Knee
Possible return date: Unknown
Alaba suffered an ACL injury against Villarreal last December, and the centre-back will not be available for the capital side until the 2024-25 campaign.
Ferland Mendy
Status: Out
Type of injury: Knee
Possible return date: April 30 (vs. Bayern Munich)
Mendy missed training on Wednesday due to a slight muscular problem, and he is not expected to play on Friday, but the defender should be back for the Champions League contest against Bayern Munich.
REAL MADRID'S SUSPENSION LIST
Real Madrid have no players banned for this match.