Kane scored his 24th Bundesliga goal in Bayern's 3-1 victory over Borussia Monchengladbach last time out but his side still trails league leaders Leverkusen by two points.
That strike edged him ever closer to Robert Lewandowski's 41-goal record, but winning a major trophy is by far the biggest prize.
Xabi Alonso's Leverkusen are still on for an invincible Bundesliga season, having needed a 94th-minute penalty equaliser from Exequiel Palacios to snatch a 2-2 draw when these sides met in September.
Bayer Leverkusen vs Bayern Munich: How to follow
This Bundesliga clash will take place on Saturday, February 10.
Kick-off at the BayArena is scheduled for 5:30pm UK time.
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The game will be broadcast on Sky Sports Football.
talkSPORT and talkSPORT.com will keep you up to date with the latest.
Bayer Leverkusen vs Bayern Munich: Team news
Odilon Kossounou continues to be unavailable for the hosts following Ivory Coast's progression to the Africa Cup of Nations semi-finals.
Leverkusen are also sweating on the fitness of absentee trio Victor Boniface, Exequiel Palacios, and Arthur.
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The visitors could hand a first start to new signing Sacha Boey, with Joshua Kimmich and Konrad Laimer both expected to miss out.
Kingsley Coman is also sidelined after picking up a knee injury.
Bayer Leverkusen vs Bayern Munich: What has been said?
Didi Hamann has told talkSPORT the level of impact Kane has had on the Bundesliga.
He told talkSPORT: "They're not playing well but it just goes to show how good he is.
"He probably touches the ball 20, 25 times and he probably scores with every third or fourth touch.
"He's settled and he's a breath of fresh air.
"To have the England captain in Germany is a huge thing and he's so humble and so likeable.
"I think for the club and the league it's been a blessing to have him."