Antonio Rudiger (muscle), Jude Bellingham (ankle), David Alaba (knee), Eder Militao (knee) and Thibaut Courtois (knee) remain unavailable for selection.
Ferland Mendy is also absent due to the milestone yellow card that he picked up in the clash with Girona last weekend, while a late check will need to be made on Brahim Diaz, who was forced off late on against RB Leipzig in the Champions League on Tuesday night.
Brahim's issue is related to his calf, but it is not thought to be serious, and there is a chance that he could be involved this weekend.
However, it seems more likely that Joselu will be brought into the side in a deeper position, as head coach Carlo Ancelotti will not want to take any risks with Brahim due to his recent form.
Fran Garcia is set to benefit from Mendy's absence, while Aurelien Tchouameni will again be required to feature in the middle of the defence alongside Nacho.
Luke Modric is pushing to be involved in midfield, but it is likely to again be Federico Valverde, Eduardo Camavinga and Toni Kroos in the positions behind the front three.
Real Madrid possible starting lineup: Lunin; Carvajal, Tchouameni, Nacho, F Garcia; Valverde, Kroos, Camavinga; Joselu; Rodrygo, Vinicius