The Gunners are top of Group B following a 4-0 win over PSV in their European opener and warmed up for this one by beating Bournemouth by the same scoreline.
Arsenal face Man City in a blockbuster top-of-the-table showdown this weekend but first must navigate their European exploits.
And the north Londoners have a real chance to put down a marker in Group B, with Lens playing out a 1-1 draw against Sevilla in week one.
Live stream: TNT Sports 2
Live commentary: talkSPORT website HERE, via the app HERE
Lens XI: Samba, Gradit, Danso, Medina, Frankowski, Mendy, Abdul Samed, Machado, Sotoca, Thomasson, Wahi.
Subs: Leca, Pandor, Aguilar, Fulgini, Diouf, Maouassa, Said, El Aynaoui, Khusanov, Guilavogui
Arsenal XI: Raya, Tomiyasu, Saliba, Gabriel, Zinchenko, Rice, Odegaard, Havertz, Trossard, Saka, Jesus.
Subs: Ramsdale, Hein, White, Partey, Smith Rowe, Nketiah, Kiwior, Cedric, Jorginho, Vieira, Nelson, Elneny.
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