The England international has been heavily linked with a move away from Spurs in the summer with his contract to expire in 2024.
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There is no indication yet on whether the 29-year-old will extend his stay, with the Red Devils understood to be circling the striker.
It was revealed earlier in the week how United were laying the groundwork to secure his services.
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And it has also been claimed Erik ten Hag's side are willing to offer him a huge pay rise to increase his salary from £200k-a-week to £300k-per-week.
United fans have clearly given the club their seal of approval to make a move for Kane after singing about the Three Lions forward during the first half.
With the visitors in cruise control in the capital, supporters sung in unison: "Harry Kane, we'll see you in June."
Though both sets of fans did see eye-to-eye in wanting to get rid of their owners as they joined together in chants against their respective board.
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Tottenham fans were furious going into the match with the club in turmoil on and off the pitch.
They vented their anger towards owners ENIC and chairman Daniel Levy ahead of the match after protesting against the board.
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And they continued to have their voices heard inside the stadium as they sang: "We want Levy out."
United supporters meanwhile chanted: "We want Glazers out."
It was another first half to forget for the hosts, as just like in their 6-1 drubbing away at Newcastle, they were outfought and outclassed.
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Though thankfully for new caretaker boss Ryan Mason, Spurs didn't go into the break 5-0 down.
Instead they trailed by just two goals, with Kane's England teammates Jadon Sancho and Marcus Rashford grabbing the goals.
Defeat for Spurs will likely end their faint chances of finishing in the top four, as they would be nine points off the top four.