But unlike in January when they made their voices heard outside the club's training ground, this time they headed to their stadium.
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Just a handful of people were in attendance at the protest in front of a sign that was strapped to a fence.
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It read: "£NIC [ENIC] out. Profit before glory."
Spurs are in turmoil on and off the pitch after suffering back-to-back defeats against Bournemouth and Newcastle.
Caretaker boss Cristian Stellini was relieved of his duties on Monday following the 6-1 drubbing at St James' Park.
Speaking to talkSPORT, one disgruntled Spurs fan at the protest said: "We've got the best stadium in the country, best stadium in the Premier League, best training facilities.
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"But we need to have the best team on the pitch, and this is where we need to focus.
"And the fans are getting very, very angry right now because we haven't won a trophy in 15 years and we want to see real action on the pitch.
"We want to see the players giving everything, on Sunday it was completely unacceptable, we went 1-0 down after 61 seconds, 5-0 after 21 minutes.
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"It was unacceptable, fans were leaving, fans are unhappy and very, very frustrated right now."
He continued: "The only optimism right now is that we might get a Europa League spot, Europa Conference League spot which most fans don't want.
"We have to put in six very, very decent performances to get results in these six remaining games to try and finish high up the table.
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"But at the moment it looks bleak, that result at Newcastle, the performance at Newcastle… we're going to face a Manchester United team who are in another final this season in the FA Cup [after winning Carabao Cup].
"And then we face Liverpool on Sunday, which is going to be another very difficult game."
Defeat against the Red Devils will likely end Spurs' faint chances of finishing in the top four.
But should they beat Erik ten Hag's side, they will jump from seventh to fifth spot, where they will trail United by just three points.