The Gunners' Premier League title charge is faltering after they followed up three consecutive draws with a 4-1 thrashing to Manchester City.
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The Blues are on an awful run of form themselves and have lost their last three league games, so Arsenal will hope to get back on track at the Emirates.
But Mikel Arteta and co will have to wait to hit back from their recent woes.
Why aren't Arsenal playing this weekend?
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Arsenal were set to welcome Chelsea to the Emirates on Saturday, April 29.
The match had been selected for live coverage by Sky Sports and was set to kick-off at 5:30pm.
However, after consultation with the Metropolitan Police and the Safety Advisory Group (SAG), the game will now take place on Tuesday, May 2.
Kick-off in north London is scheduled for 8pm.
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The Met Police were initially prepared to supply enough police officers for the match but have revised their position after discussions with SAG.
The initial scheduling was approved in February but has been changed at short notice.
In a statement, Arsenal said: "The Premier League has announced that our home league match against Chelsea will now take place on Tuesday, May 2 kicking off at 8pm.
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"This change has been made as a result of the Metropolitan Police revising its position on policing the match.
"After working to try to find a solution with the Met Police, we are very disappointed with the impact and disruption this fixture change will cause to our supporters, particularly after this match had been initially approved for a Saturday evening kick-off."
The Premier League also released a statement of their own, in which they said: "The Premier League fixture between Arsenal FC and Chelsea FC at Emirates Stadium, scheduled to take place on Saturday, 29 April at 5.30pm, will now take place on Tuesday, 2 May at 8.00pm.
"The initial scheduling of this match was approved at a Safety Advisory Group (SAG) meeting in February.
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"However, the Metropolitan Police has now revised its position regarding the kick-off time and requested a further SAG meeting which determined the match had to be rescheduled.
"We regret the need to move this fixture at late notice and the impact this will have on supporters.
"The game will remain live on Sky Sports."