The Yanks have triumphed in their last two exhibition games over Uzbekistan and Oman by an aggregate score of 7-0, while Die Mannschaft saw off France under the temporary tutelage of Rudi Voller last time out.
Match preview
While the USA's upcoming visitors are entering a new managerial epoch, the Yanks have been reacclimatising to life under World Cup coach Gregg Berhalter, who returned to the hotseat over the summer following a troubled few months of off-field controversies.
During Berhalter's sabbatical, B.J. Callaghan secured CONCACAF Nations League glory with the USA before overseeing the defence of their Gold Cup crown, which ended in semi-final penalty heartbreak to Panama, and the 42-year-old subsequently handed the reins back over to Berhalter.
A pair of home friendlies with Uzbekistan and Oman represented a kind second baptism for Berhalter, whose side hit the former for three without reply before putting four unanswered goals past Oman thanks to Folarin Balogun, Ricardo Pepi, Brenden Aaronson and a Khalid Al-Braiki own goal.
Receiving a bye into the quarter-finals of the ongoing CONCACAF Nations League, the USA - whose last-eight opponents are yet to be determined - will also warm up for their return to competitive action with a friendly against Ghana next week, as Berhalter's men endeavour to prolong their golden streak in front of goal.
Indeed, the Stars and Stripes have found the back of the net in each of their last 12 fixtures across all tournaments since a goalless stalemate with Colombia in January, while only six goals have flown past them at the other end of the field across their last 14 friendly home contests.
Unparalleled domestic success with Bayern Munich did not translate into international stardom for ex-Germany boss Hansi Flick, who oversaw a disastrous period of spring and summer time friendlies in the wake of another premature World Cup exit for Die Mannschaft.
Alongside a captivating 3-3 stalemate with Ukraine, all of Belgium, Colombia, Poland and Japan - the latter of whom stormed to a 4-1 crushing - put the Euro 2024 hosts to the sword, and that final embarrassing loss to the Samurai Blue unsurprisingly proved to be the final nail in Flick's coffin.
Legendary marksman Rudi Voller was placed in temporary charge for last month's visit of France to the Signal Iduna Park, where Germany experienced the true meaning of a new manager bounce, defeating the 2022 World Cup runners-up 2-1 courtesy of Thomas Muller and Leroy Sane's efforts.
Voller and his 100% record now make way for fresh blood in Nagelsmann, who was linked with a host of European powerhouses before assuming office in his homeland, and the ex-Bayern head coach will also lead Die Mannschaft into another exhibition contest with Mexico in Philadelphia later this month.
Antoine Griezmann's late consolation for France in September means it is now six games without a clean sheet for Germany, though, and the USA have actually prevailed in back-to-back friendlies with Die Mannschaft either side of a 1-0 World Cup 2014 loss, most recently triumphing 2-1 in June 2015 under another one of the visitors' favourite sons, Jurgen Klinsmann.
USA friendly form:
D
W
W
USA form (all competitions):
W
W
W
L
W
W
Germany friendly form:
L
D
L
L
L
W
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Team News
German-born attacker Malik Tillman - who now plies his trade with PSV Eindhoven - will not have the chance to build on the six caps he has already won for his nation this month, as the 21-year-old withdrew from the squad with a minor injury earlier this week.
Tillman joins a lengthy list of notable absentees, which also includes Antonee Robinson, Tyler Adams and Zack Steffen, while Borussia Dortmund protege Giovanni Reyna has been called up but is not expected to be thrown back into the deep end as he builds up his match fitness.
As such, Aaronson could potentially earn a midfield start alongside Yunus Musah and Weston McKennie in the trident, while in-form Monaco new boy Balogun enters the October break on the back of registering four goal contributions in his last four Ligue 1 appearances, three of his own and one assist.
Similarly, Germany head coach Nagelsmann is also working around a surfeit of injuries ahead of his inaugural fixture, as none of Serge Gnabry, Manuel Neuer, Matthias Ginter or Benjamin Henrichs were available for selection, while Timo Werner, Nico Schlotterbeck and Emre Can have been overlooked.
However, the Mannschaft manager has called upon a quartet of uncapped names - notably rewarding Union Berlin hotshot Kevin Behrens with a maiden call-up - while Oliver Baumann, Robert Andrich and Chris Fuhrich are also eyeing their first minutes for the national team.
Spots on the bench most likely await each of the four fringe players, though, as Nagelsmann reunites captain Ilkay Gundogan with Joshua Kimmich in midfield, and the 36-year-old is said to have tested out a 4-2-2-2 setup during his earliest training sessions.
USA possible starting lineup:
Turner; Dest, Robinson, Richards, Lund; McKennie, Musah, Aaronson; Weah, Balogun, Pulisic
Germany possible starting lineup:
Ter Stegen; Thiaw, Sule, Rudiger, Raum; Kimmich, Gundogan; Sane, Musiala; Fullkrug, Muller
We say: USA 1-2 Germany
A change in management worked wonders for Germany when France made a brief stopover last month, and while Nagelsmann may take some time to fully implement his methods, Die Mannschaft can fight fire with fire to get off to the perfect start under the 36-year-old.