How Manchester United could line up against Brighton & Hove Albion

After picking up a foot injury in the Red Devils' 3-1 defeat at Arsenal before the international break, the 25-year-old was not involved in either of Argentina's CONMEBOL World Cup qualifiers, but he was fit to train with the national team and could therefore feature in defence against the Seagulls.

Mason Mount could also return to the matchday squad after nearly a month out with a hamstring problem, while fellow summer signing Sofyan Amrabat is a major doubt with a back issue and is unlikely to be risked by manager Erik ten Hag.

The Moroccan midfielder may therefore join Raphael Varane (muscle), Luke Shaw (muscle), Tyrell Malacia (muscle), Amad Diallo (knee), Kobbie Mainoo (ankle) and Tom Heaton (calf) in the treatment room, while Antony will not represent the club 'until further notice' amid allegations of assault made against him.

Victor Lindelof came off in the loss at Arsenal due to illness, but the Swedish defender is fit to start on Saturday and could play alongside Martinez at centre-back, pending a late fitness check, while Harry Maguire and Jonny Evans are both backup options available to Ten Hag. Meanwhile, Sergio Reguilon could be handed his debut at left-back after joining on loan from Tottenham Hotspur, although Diogo Dalot impressed on the left side against Arsenal and may keep his starting spot.

Casemiro, Christian Eriksen and Bruno Fernandes are the most likely trio to play in midfield, although the latter is an option to start on the right flank now that Antony is ruled out and Jadon Sancho - who experienced an off-field feud with Ten Hag during the international break - is not expected to be involved.

Facundo Pellistri is another player who could feature on the right as well as Alejandro Garnacho, while Marcus Rashford is expected to continue on his favoured left side of attack with either Anthony Martial or Rasmus Hojlund set to start up front, the former of whom is hoping to make his full debut after coming on as a second-half substitute against Arsenal.

Manchester United possible starting lineup: Onana; Wan-Bissaka, Lindelof, Martinez, Dalot; Casemiro, Eriksen; Garnacho, Fernandes, Rashford; Hojlund