Eberechi Eze, Jefferson Lerma and Chris Richards are all sidelined with hamstring injuries and are joined in the treatment room by Adam Wharton (groin), Chadi Riad (knee) and Matheus Franca (groin).
Eddie Nketiah is understood to have picked up a minor hamstring issue and has emerged as a doubt, while Joel Ward could be ready to return to the matchday squad after a spell out with an unspecified problem.
Oliver Glasner is expected to name a similar side to the one that drew 2-2 with Wolverhampton Wanderers last weekend. Trevoh Chalobah and captain Marc Guehi both scored in that match and are set to continue in central defence alongside Maxence Lacroix.
Daniel Munoz and Tyrick Mitchell are expected to operate as wing-backs once again, while midfielder Cheick Doucoure could be fit to start his first league game since mid-September at the expense of either Will Hughes or Daichi Kamada.
The latter, however, could be pushed further forward if Nketiah is not deemed fit to feature and link up with Ismaila Sarr and Jean-Philippe Mateta in attack.
Crystal Palace possible starting lineup: Henderson; Chalobah, Lacroix, Guehi; Munoz, Doucoure, Hughes, Mitchell; Sarr, Kamada; Mateta
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