Jose Mourinho's side have been poor in recent weeks and lost to Leicester last Sunday.
They need to bounce back but face a tricky trip to the West Midlands today.
Wolves also lost last time out, going down 2-1 at Burnley, but can move into the top half of the table with a win.
Wolves v Tottenham: How to watch
This match will be held at Molineux on Sunday, December 27 and will kick-off at 7:15pm.
It is being broadcast on Sky Sports Main Event and Sky Sports Premier League from 7pm and follows their coverage of Liverpool v West Brom.
Sky Sports customers can live stream this via the app using their mobile, tablet or computer devices.
If not, you can purchase a Sky Sports Day Pass from NowTV for £8.99.
Wolves v Tottenham: Team news
Wolves hope Leander Dendoncker and Willy Boly will be available for the visit of Tottenham.
Belgium midfielder Dendoncker missed Monday's 2-1 defeat at Burnley after picking up an injury in the previous game against Chelsea.
Boly was an unused substitute at Turf Moor and should return, but Raul Jimenez and Jonny remain sidelined.
Tottenham, meanwhile, will be without Giovani Lo Celso due to a hamstring injury which will keep him out for the festive period.
Gareth Bale will be assessed after he came off at half-time during the Carabao Cup quarter-final win at Stoke with a calf problem, having given his side the first-half lead.
Japhet Tanganga will also miss out for Jose Mourinho's team with his shoulder issue.
Wolves v Tottenham: What has been said?
Tottenham boss Jose Mourinho: "It is very hard in this league to have consistent runs because every game is very difficult.
"We were in a period where we had to play against the considered top six teams where we got them in a row and some people can say now we are going to get an easier run of matches.
"What is easier? Go to Wolves and play Fulham and Leeds? It's not easier, this is a league where we are and we should be very happy with that and not sad with that.
"We should be happy because it is a fantastic league."
On compatriot Nuno Espirito Santo, Mourinho said: "Nuno is a very good coach it doesn't matter if Wolves are second, third, eighth or ninth.
"I think this is a question I answer for three years in a row, every time I play Wolves this question comes.
"You just need to copy and paste what I say. Very good coach, great work, the results are there. You know my answer he is a very good coach."
Wolves v Tottenham: Match stats and facts
Following their 3-2 win at Spurs in the last Premier League meeting between the sides, Wolves are looking to secure back-to-back league wins against them for the first time since the 2009-10 campaign, when they completed a league double over them.
Spurs have won each of their last three Premier League away games against Wolves, netting at least twice each time. Indeed, just one of Spurs' four Premier League defeats to Wolves has come at Molineux (0-1 in February 2010).
Since their return to the Premier League in 2018, Wolves have won 17 of their 19 Premier League home games when scoring the first goal, drawing the other two.
Tottenham have lost their last two Premier League games, as many as they had in their previous 22 in the competition (W12 D8). Spurs haven't lost three consecutive league games since November 2012 under André Villas-Boas.
After winning their first four Premier League away games this season, Spurs are winless in their last three on the road (D2 L1). However, they're yet to lose consecutive away league games under José Mourinho.
Having netted 15 goals in their first five Premier League games this season (3 per game), Tottenham have netted just 10 in their last nine in the competition (1.1 per game). 20 of their 25 league goals this season (80%) have been scored by either Son Heung-min (11) or Harry Kane (9).
Wolves haven't kept a clean sheet in any of their last seven Premier League games (W2 D1 L4), having shut their opponents out in four of their first seven this season (W4 D1 L2).
Since their return to the Premier League in 2018, Wolves average just 0.7 goals per Premier League game without Raúl Jiménez in the starting lineup, compared to 1.3 goals-per-game when the Mexican does start.
Tottenham's Harry Kane has scored nine Premier League goals this season; his next strike will see him become just the fourth Englishman to reach double figures in seven consecutive Premier League campaigns, after Michael Owen (97-98 to 03-04), Frank Lampard (10 between 03-04 and 12-13) and Wayne Rooney (11 between 04-05 and 14-15).
Gareth Bale has never scored in six previous league appearances against Wolves (5 with Spurs, 1 with Southampton). The Welshman has only faced Everton (8) more without finding the net in English league football.
Wolves host Tottenham this evening as Spurs look to hit back from their recent dip in form.