Ange Postecoglou's men fought back from a goal down to sink London rivals Brentford 3-2 in a midweek thriller, where Destiny Udogie, Brennan Johnson and Richarlison found the mark.
Owing to Aston Villa's loss to Newcastle United 24 hours beforehand, Spurs have leapfrogged the Lions in the rankings, although they are only better off than Unai Emery's side on goal difference.
Here, Sports Mole rounds up their latest injury and suspension news ahead of the clash with Everton, whose midweek clash with Fulham ended goalless.
Manor Solomon
Status: Out
Type of injury: Knee
Possible return date: Unknown
Following previous optimism over a January comeback, Postecoglou revealed that Manor Solomon had suffered a pair of setbacks in his recovery from a knee concern, and there is still no indication when he might be playing again.
Alfie Whiteman
Status: Out
Type of injury: Ankle
Possible return date: Unknown
Backup goalkeeper Alfie Whiteman is still on the mend from a serious ankle problem, but the Englishman would only be making the bench in the Premier League anyway.
Alejo Veliz
Status: Out
Type of injury: Knee
Possible return date: March 2 (vs. Crystal Palace)
Alejo Veliz is still facing a few more weeks out with the knee injury he picked up against Bournemouth on New Year's Eve, but should his rehabilitation go to plan, he will be back on the field in early March.
Giovani Lo Celso
Status: Out
Type of injury: Hamstring
Possible return date: February 10 (vs. Brighton & Hove Albion)
There was hope that Giovani Lo Celso's hamstring issue would clear up in time for the clash with Brentford, but he ultimately did not make the cut, and Saturday's game should also come too soon for the Argentine.
Son Heung-min
Status: Out
Possible return date: Unknown
Son Heung-min's South Korea are currently gearing up for their Asian Cup quarter-final with Australia on Friday, meaning that Spurs will cope without their captain for at least one more match.
Pape Sarr
Status: Minor doubt
Possible return date: February 3 (vs. Everton)
In contrast, Senegal's Africa Cup of Nations run ended with a penalty-shootout loss to Ivory Coast in Monday's last-16 fixture, so Pape Sarr will be expected to return to domestic duty this weekend in a significant boost for Postecoglou and co.
Yves Bissouma
Status: Out
Possible return date: Unknown
By overcoming Senegal, Ivory Coast set up a quarter-final tie with Yves Bissouma's Mali, therefore rendering the former Brighton & Hove Albion man unavailable for the trip to Everton as well.
Ryan Sessegnon
Status: Out
Type of injury: Hamstring
Possible return date: Unknown
After only just battling back from a summer hamstring operation, Ryan Sessegnon returned to the infirmary with a slight recurrence of the injury, and it is not clear when the former Fulham winger might be back at Postecoglou's disposal.
TOTTENHAM HOTSPUR'S SUSPENSION LIST
Tottenham have no players suspended for this match.