Carlo Ancelotti's side are top of the La Liga table on 24 points, but a disappointing campaign to date has left Sevilla down in 14th spot, and here Sports Mole rounds up the team news.
SEVILLA vs. REAL MADRID
SEVILLA
Out: Mariano Diaz (muscle), Marko Dmitrovic (knee), Erik Lamela (muscle), Alfonso Pastor (knee)
Doubtful: Fernando (muscle)
Sports Mole's predicted XI: Nyland; Navas, Bade, Ramos, Pedrosa; Rakitic, Sow; Ocampos, Suso, Lukebakio; En-Nesyri
REAL MADRID
Out: Nacho (suspended), Eder Militao (knee), Thibaut Courtois (knee), Dani Ceballos (muscle), Arda Guler (thigh)
Doubtful: None
Sports Mole's predicted XI: Kepa; Carvajal, Rudiger, Alaba, Camavinga; Valverde, Tchouameni, Kroos; Bellingham; Joselu, Vinicius
For data analysis of the most likely results, scorelines and more for this match please click here.