Cristiano Ronaldo threw a strop when he was subbed before the hour mark when Manchester United beat City 2-0 in the derby at Old Trafford in 2009.
Ronaldo scored the opener, with Carlos Tevez claiming the second, as Sir Alex Ferguson's side took a big step towards the Premier League title with the win.
Portugal star Ronaldo, who was to leave United for Real Madrid that summer in a then-world record £80million deal, was furious at making way for Paul Scholes.
Ronaldo stood by the side of the pitch in disbelief at the decision, before angrily swiping away a tracksuit top that was being held out for him by a member of United's backroom staff.
Ronaldo continued his public show of dismay, shaking his head in disgust as he took his seat in the dugout with the rest of the subs.
Although United would go on to win the title, they lost the Champions League final 2-0 to Barcelona 17 days later, in what was Ronaldo's last game before his move to Real.
Ronaldo may be back at United for a second spell, but ahead of Sunday's derby at the Etihad Stadium, we take a look at where his team-mates from that derby day are now.
Edwin van der Sar: Now chief executive of Ajax, where he began his playing career. Van der Sar, 51, has been touted as a potential CEO of United, such is his standing within the game.
Rafael Da Silva : Right-back, 31, left United in 2015, a year after his twin Fabio, to join Lyon, then had a stint playing in Turkey. Now back in his native Brazil, playing for Botafogo.
Nemanja Vidic: After eight years and 300 appearances for United, Vidic, now 40, left in 2015 and spent two years at Inter, before retiring from playing and completing his coaching badges.
Jonny Evans: Left United in 2015 for West Brom, where he spent three years, then joined Leicester, where the 34-year-old remains, although he is currently sidelined by injury.
Patrice Evra: Had stints at Juventus, Marseille and West Ham after leaving United in 2014. The 40-year-old recently wrote his autobiography and appears as a Sky Sports pundit from time to time.
Darren Fletcher: The former midfielder, 38, is now United's Technical Director, focusing on developing academy talent to bring through to the first-team, but is often in the dugout on match-days.
Ryan Giggs: United's record appearance holder, 48 became Wales boss, but stepped aside last year following his arrest.
Was subsequently charged with actual bodily harm, common assault and coercive and controlling behaviour, for which he will go on trial in August. Giggs denies all the charges.
Park Ji-Sung: Now retired, the former South Korea star, 40, who won four Premier League titles and the Champions League with United, took up a coaching role with the Under-16 side at Queen's Park Rangers last December.
Dimitar Berbatov: After four years at United, Berbatov left in 2012 and retired seven years later. Now 41, he has a commercial tie-up with Betfair, for whom he is an ambassador.
Carlos Tevez: Spent two years at United before controversially signing for City in what was an acrimonious move across Manchester. Now 38, he last played for Boca Juniors in Argentina last year.
Cristiano Ronaldo: Five-time Ballon d'Or winner, 37, is now back at United for a second stint, after a glittering nine-year spell at Real Madrid, followed by three full seasons at Juventus.
Subs
John O'Shea: Left United in 2011 for Sunderland, where he spent eight years. Now 40, had a brief spell at Reading, where he is now a coach.
Wayne Rooney: United's record goalscorer, 36, who scored 253 times in 13 years at Old Trafford, is now manager at Championship club Derby.
Paul Scholes: Third on United's all-time appearances list with 718 games, Scholes, 47, is now a pundit for BT Sport and a co-owner of Salford City.