Los Blancos clash with the Blues on the back of a 2-1 loss to Barcelona in El Clasico, where Vinicius Junior and Rodrygo were both on the bench after their Copa America exploits, and the former was brought on for the final half-hour.
With limited recovery time in between friendlies, Carlo Ancelotti might be tempted to promote Vinicius and Rodrygo to the starting lineup, where they will line up alongside compatriot Endrick.
Arda Guler and Brahim Diaz started in the final third in El Clasico, but the former could still keep his place; Luka Modric played the full 90 at the weekend and might be granted a well-earned rest.
Mario Martin and Dani Ceballos are in line to join Guler in the midfield trident, while Antonio Rudiger and Thibaut Courtois should both be involved from the off against their old employers.
Eder Militao, Lucas Vazquez and Fran Garcia should complete an untouched defensive quintet for the European champions, who are still without David Alaba as he recovers from his ACL injury.
In addition, Federico Valverde, Jude Bellingham, Dani Carvajal, Ferland Mendy, Aurelien Tchouameni, Kylian Mbappe and Eduardo Camavinga are still on holiday after their international exploits.
Real Madrid possible starting lineup:
Courtois; Vazquez, Militao, Rudiger, Garcia; Guler, Martin, Ceballos; Rodrygo, Endrick, Vinicius Jr