While the Championship side have already got two games under their belt, the Spanish outfit will be participating in their first fixture of the summer.
Match preview
After a solid first six months in charge at Preston, Ryan Lowe has taken the opportunity to make some shrewd additions ahead of the new season.
The acquisition of Newcastle United goalkeeper Freddie Woodman could prove to be a difference maker, as could adding Robbie Brady to their options on the left flank.
On the back of playing 28 games for Hearts in the Scottish Premiership, Deepdale feels like a good destination for forward Ben Woodburn to continue to reignite his career.
With there having been more senior departures than incomings, further signings will follow, and there is optimism at the North-West side that they can mount a bid for the playoffs this time around.
Having opened the summer with a 3-0 win over Bamber Bridge, Preston went down 1-0 to Tranmere Rovers in a behind-closed-doors friendly on July 5.
As a result of their season not starting until the middle of August, Getafe will be playing their first encounter of the summer.
A 15th-placed finish in La Liga during 2021-22 means that Quique Sanchez Flores is under pressure to deliver a much-improved campaign.
The Spaniard's transfer business has been minimal thus far with the loan addition of Real Sociedad playmaker Portu having the potential to improve matters in the final third.
After this fixture, the remainder of Getafe's pre-season schedule takes place against Spanish opposition before they begin La Liga at home to Atletico Madrid.
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Team News
While Lowe may be tempted to name his strongest Preston side for this fixture, some players earned more game time than others against Tranmere.
Ben Whiteman and Woodburn came through over 70 minutes, and preference may be given to numerous squad members who only played 45 minutes.
Woodman and fellow new goalkeeping arrival David Worrall played a half each, but the former could spend more time on the pitch in Spain.
With this game being their first of a six-game schedule, Getafe's starting lineup is a complete unknown with Flores no doubt wanting to ease his squad back into action.
Nemanja Maksimovic and Enes Unal were part of the Serbia and Turkey squads in UEFA Nations League action up until the middle of July, meaning that they could miss out here.
We say: Getafe 1-1 Preston North End
Having already got some game time in their legs, Preston will fancy their chances of causing the upset in Campoamor. However, the climate may be better suited to the Spaniards, leading us to predict a relatively-uneventful 1-1 draw.