That is one of two blockbuster clashes on Saturday evening, with Tottenham Hotspur also hosting Manchester United, while Liverpool entertain Bournemouth on a bumper second Saturday of the 2023-24 campaign.
Sunday brings a London derby between West Ham United and Chelsea, while there is another capital contest on Monday night as Arsenal travel to Crystal Palace.
There will only be nine games this weekend due to Luton Town's match with Burnley being postponed because their ground is not ready yet for the top flight, but the other promoted team - Sheffield United - help kick things off on Friday night against Nottingham Forest.
Each gameweek, Sports Mole is taking on a famous musician or band in a prediction competition, and this week it is the turn of singer-songwriter - and Liverpool fan - Tom Speight.
Nottingham Forest vs. Sheffield United
Friday, 7.45pm
Tom: Nottingham Forest 2-1 Sheffield United
Sports Mole: Nottingham Forest 2-1 Sheffield United
Fulham vs. Brentford
Saturday, 3pm
Tom: Fulham 0-1 Brentford
Sports Mole: Fulham 0-2 Brentford
Liverpool vs. Bournemouth
Saturday, 3pm
Tom: Liverpool 2-0 Bournemouth
Sports Mole: Liverpool 3-1 Bournemouth
Wolverhampton Wanderers vs. Brighton & Hove Albion
Saturday, 3pm
Tom: Wolves 0-0 Brighton
Sports Mole: Wolves 1-2 Brighton
Spurs vs. Manchester United
Saturday, 5.30pm
Tom's prediction: Spurs 1-1 Man United
Sports Mole's prediction: Spurs 2-1 Man United
Manchester City vs. Newcastle United
Saturday, 8pm
Tom's prediction: Man City 3-1 Newcastle
Sports Mole's prediction: Man City 3-2 Newcastle
Aston Villa vs. Everton
Sunday, 2pm
Tom's prediction: Aston Villa 0-1 Everton
Sports Mole's prediction: TBC
West Ham United vs. Chelsea
Sunday, 4.30pm
Tom's prediction: West Ham 1-2 Chelsea
Sports Mole's prediction: TBC
Crystal Palace vs. Arsenal
Monday, 8pm
Tom's prediction: Crystal Palace 1-3 Arsenal
Sports Mole's prediction: TBC
Tom Speight Q&A
How did you come to support Liverpool and what are your favourite memories from your time as a fan?
"I first started supporting Liverpool when I was eight years old during the 'Spice Boys-era'. My dad got me the kit and left me no choice. Personally, my favourite memory is 100% when I got to meet Robbie Fowler in person."
Who have been your favourite five players for your club (historically or currently)?
"John Barnes is my all time favourite! But I also love Steven Gerrard, Fowler, Mohamed Salah and Ian Rush."
What's going on for you as an artist at the moment?
"My album 'Love & Light' us out. It should hopefully be able to soundtrack the most joyous of victories and hard times. It's got a bit of everything on it. I can't wait to tour it in September/October."
Tom Speight's new song 'Trick Of The Light' is available to stream now.
You can follow Tom Speight on Instagram and Twitter.
2023-24 SEASON LEADERBOARD (ARTISTS)
Scores are calculated as one point for a correct result and five points for a correct scoreline.
1. Insincere (4pts | Gameweek 1)
2023-24 COMPETITION HISTORY
Gameweek 1: Insincere 4-16 Sports Mole
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