The 39-year-old's international future was in severe doubt after the 2022 World Cup, but he has been a vital player under the management of Roberto Martinez, finding the back of the net on 10 occasions during the nation's qualification campaign for Euro 2024.
Portugal will play three warm-up games ahead of the European Championship, also tackling Croatia and the Republic of Ireland, so Martinez will be making the most of his squad.
Rafael Leao and Diogo Jota could also earn starts on Tuesday, while Bruno Fernandes will feature in midfield off the back of helping Manchester United win the FA Cup.
Manchester City trio Joao Cancelo, Ruben Dias and Bernardo Silva are also expected to be among the starters for Portugal in this contest.
Diogo Costa could be given the nod in goal, while 41-year-old Pepe is bidding to feature in the middle of the defence, with Diogo Dalot potentially operating at left-back.
Joao Palhinha is likely to be the holder in the Portugal midfield, but there will be changes over the course of the match, with Ruben Neves, Vitinha and Joao Neves also pushing to be involved.
Francisco Conceicao will also be bidding to make his second appearance for the national side.
Portugal possible starting lineup: Costa; Cancelo, Pepe, Dias, Dalot; Fernandes, Palhinha, Bernardo; Leao, Ronaldo, Jota