The home side are winless after two matches, picking one point from six, but they hope to end their winless start this weekend.
Match preview
Luzern have had a false start to their league campaign after losing on the opening day to Servette before drawing against Grasshopper Zurich in gameweek two.
The previous league fixture ended positively for Mario Frick's men, who recovered from falling behind 2-1 to peg back the Hoppers in the final five minutes.
Die Leuchten return to Swissporarena keen to bounce back from their opening-day loss to Servette to record their first victory of the new campaign at the third time of asking.
Dating to last season, Frick's men have notched one victory in their last 10 league matches, underlining the team's extended slide in performances and results.
With only one home top-flight victory secured in the last nine on home turf, Luzern supporters may not be optimistic heading into round three this weekend.
In-form Sion have had a perfect start to the new term since regaining promotion and aim to inflict more pain on a side that carried last season's underwhelming results into the 2024-25 campaign.
A 2-1 success at Young Boys was followed by a 4-0 thrashing of Lausanne-Sport last weekend, a result underscored by two early goals and a pair of late ones for Didier Tholot's men.
As a consequence of both wins, Sion are one of four sides to have won every game played this season, with Servette notching three wins in that period, and they seek to extend their winning start.
Having already defeated defending champions Young Boys in round one, Tholot's men aim to notch another triumph to keep their run going and possibly leapfrog Servette if results elsewhere go their way.
Despite their outstanding start, the last four meetings between both clubs have been split, suggesting that Saturday's match could go either way.
Luzern Swiss Super League form:
L
D
Sion Swiss Super League form:
W
W
Team News
Ismajl Beka is expected to miss the entirety of the 24-25 campaign due to a serious knee injury, while Joaquin Ardaiz is anticipated to return in a few weeks.
Sofyan Chader is carrying a knock for Luzern, and the forward's participation on Saturday is uncertain.
Having notched two of the home side's three league goals, Lars Villiger seeks to make the desired impact for a side chasing their first victory.
Reto Ziegler is Sion's only injury doubt for Saturday, as the defender is struggling with a knee injury.
The visitors have had six different goalscorers this term, with Numa Lavanchy, Theo Berdates, Yiyas Chouaref, Ali Kabacalman, Cristian Souza and Dejan Dokic all finding the net for Tholot's unblemished men.
Luzern possible starting lineup:
Loretz; Ulrich, Jaquez, Lofgren, Knezevic, Ciganiks; Dorn, Stankovic, Kadak; Villiger, Karweina
Sion possible starting lineup:
Fayulu; Lavanchy, Schmeid, Diouf, Hefti; Berdayes, Kabacalman, Costa, Bouchlarhem; Chouaref, Sorgic