The trio were not involved in the team's 1-0 defeat to AC Milan last time out, having represented Brazil at this summer's Copa America, but they are set to be available to play a part in El Clasico.
Dani Carvajal, Jude Bellingham, Eduardo Camavinga, Aurelien Tchouameni, Ferland Mendy and Federico Valverde will not be involved in the United States, though, due to international commitments.
The same can also be said for Kylian Mbappe, who has been given an extended break after representing France at this summer's European Championship.
There was a Los Blancos debutant against Milan, though, with Endrick playing the opening 45 minutes of what proved to be a 1-0 loss for the European champions.
Endrick is again likely to lead the line, with Arda Guler and Brahim Diaz also set to keep their spots in the final third of the field.
Jesus Vallejo should retain his spot in the middle of the defence, while Fran Garcia and Dani Ceballos are also expected to be among the starters for Carlo Ancelotti's side in the glamour friendly.
There will be no Cesar Palacios, though, as the 19-year-old, who came off the bench against Milan, is returning to Spain after suffering a severe knee injury.
Real Madrid possible starting lineup: Courtois; Vazquez, Vallejo, Rudiger, F Garcia; Modric, Martin, Ceballos; Guler, Endrick, Diaz
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