The visitors' eight-match unbeaten run came to an end last time out, while their hosts are still searching for their first win in 11 matches.
Match preview
Atletico Goianiense were unable to hold on to an early lead, conceding with just two minutes remaining in normal time to draw 1-1 with Vasco da Gama in the first leg of their Copa do Brasil round-of-16 tie.
Vagner Mancini's side are without a win in their last 12 matches across all competitions, with 11 of those coming in the Serie A.
Dragao suffered a 2-0 defeat against league leaders Flamengo in their most recent league match, leaving them with seven defeats and four draws since their victory over Fluminense on 16 June.
Goianiense remain rooted to the bottom of the Serie A table with 12 points from 20 matches, leaving them six points adrift of safety and facing a strong possibility of relegation back to Serie B for the second time in three years.
Things are not getting any easier for Goias' side, as they host one of the league's best teams next, having failed to record a home win in the league so far.
Botafogo have struggled to pick up victories in recent times, with their most recent win coming in a 1-1 draw at home against Bahia in the first leg of their Copa do Brasil round-of-16 tie.
Before that, Artur Jorge's side were unable to extend their unbeaten run in the Serie A to nine games, suffering a shock 3-0 defeat at home to Cruzeiro last Saturday.
This defeat saw Fogo relinquish top spot in the league, as they now sit in second place but are level on 40 points with leaders Flamengo, having played one game more.
Botafogo are back on the road for this clash, aiming to extend their away unbeaten run to five matches, having won and drawn each of the last four.
Jorge's side have the joint-most points away from home, and they also have an ongoing five-match unbeaten streak in their visits to Atletico Goianiense, although the last four have ended in draws.
Atletico Goianiense Brasileiro form:
L
L
L
L
D
L
Atletico Goianiense form (all competitions):
L
L
L
D
L
D
Botafogo Brasileiro form:
W
W
W
D
D
L
Botafogo form (all competitions):
W
W
D
D
L
D
Team News
Goianiense will remain without 29-year-old defender Bruno Tubarao, who is set to miss out due to a thigh injury he picked up against Palmeiras on July 11.
Attacking midfielder Angelo Araos is also sidelined with a cruciate ligament tear, and is not expected to return until late September.
Botafogo will remain without the services of Gatito Fernandez and new signing Thiago Almada, who are away at the ongoing Olympics with Paraguay and Argentina respectively.
The visitors will also be missing Rafael da Silva (knee), Philipe Sampaio (knock), Carlos Eduardo (thigh), Matheus Nascimento (hamstring) and Junior Santos (ankle) who will all remain on the sidelines.
Left-winger Jeffinho and defender Pablo are also recovering from knee and thigh injuries respectively and are also unavailable for selection.
Atletico Goianiense possible starting lineup:
Rangel; Roni, Martins, Alix, Romao; Freitas, Rhaldney, Baralhas; Janderson, Hurtado, Fernando
Botafogo possible starting lineup:
John; Suarez, Bastos, Halter, Cuiabano; Henrique, Freitas, Barbosa, Tche; Soares, Savarino