Since a dismal 3-1 home loss to Lorient, PSG have suspended Lionel Messi for two weeks after the Argentine took an unauthorised commercial trip to Saudi Arabia, meaning that he may well have played his final game in a Parisiens jersey.
Achraf Hakimi must also serve a one-game ban for his sending off last weekend, while Nuno Mendes has picked up a season-ending hamstring problem, joining Neymar (ankle), Presnel Kimpembe (Achilles) and Nordi Mukiele (hamstring) on the long-term absentee list.
Timothee Pembele is also recovering from a knee problem, so unless Galtier reverts Sergio Ramos to the right-back role from the embryonic stages of his career, the PSG boss is facing a crisis in that area of the field.
With Ramos, Marquinhos and Danilo Pereira likely forming a three-man wall in front of Gianluigi Donnarumma, Galtier may bring in Warren Zaire-Emery as a makeshift wing-back, having previously deployed the 16-year-old on the right-hand side against Bayern Munich in the Champions League. Juan Bernat will continue on the left in place of the stricken Mendes.
Renato Sanches has been seen on the training pitches as he recovers from a groin issue, but the Portuguese should not be risked from the off as Marco Verratti, Vitinha and Fabian Ruiz - who could replace Carlos Soler - start from the opening whistle.
As Messi watches on from the naughty step, Reims loanee Hugo Ekitike is now poised to earn a rare start in the final third alongside Kylian Mbappe.
Paris Saint-Germain possible starting lineup: Donnarumma; Pereira, Marquinhos, Ramos; Zaire-Emery, Verratti, Vitinha, Ruiz, Bernat; Mbappe, Ekitike