How Barcelona could line up against Atletico Madrid

Ousmane Dembele, Sergio Aguero, Jordi Alba and Martin Braithwaite will definitely miss the match, while Alejandro Balde remains a doubt due to an ongoing back problem.

There will be changes from the side that lost 3-0 to Benfica in the Champions League, and it would not be a surprise to see the Catalan outfit revert to a four-man defence, potentially matching up to Atletico.

Gerard Pique was substituted in the first half of the game against Benfica, but it was a tactical decision rather than an enforced alteration, and the Spaniard should be in the XI for this game.

Sergi Roberto and Sergino Dest are likely to operate in the full-back areas, while a strong midfield could include Frenkie de Jong, Sergio Busquets and Pedri, who are all available.

It will be fascinating to see what Koeman has in mind for the attacking positions; Memphis Depay is a certain starter, but the other two positions are open.

Ansu Fati is not expected to be considered for a start, having only just returned from a long-term knee problem, so there could be an opportunity in the final third of the field for Philippe Coutinho.

Koeman has also favoured playing with a centre-forward this season, and it would therefore not be a surprise to see Luuk de Jong again feature at the tip of the attack.

Barcelona possible starting lineup: Ter Stegen; Roberto, Pique, Araujo, Dest; F de Jong, Busquets, Pedri; Memphis, L de Jong, Coutinho