Spurs cut ties with Nuno Espirito Santo just 17 games into his tenure on Monday.
And the club have moved quickly to bring in ex-Chelsea chief and perennial winner Conte.
The enigmatic - and at times divisive - Italian has said he is 'extremely happy' to take over in north London and is excited to bring his 'passion, mentality and determination' to the club.
Tottenham fans will be hoping and praying that Conte is the man to finally end their long wait for a trophy.
In an ironic twist of fate, Conte's unveiling comes on an unwanted anniversary for the club.
Today marks 5,000 days since Tottenham last lifted a trophy.
That was their League Cup success in the 2007/08 season when Tottenham beat Chelsea 2-1 in extra-time at Wembley on February 24, 2008.
Prior to that, Spurs' most recent silverware win was claiming FA Cup glory over Nottingham Forest in 1991.
Conte has a proven track record for success having won league titles in England and Italy and he'll be eager to turn things around at Tottenham.
He said: "I am extremely happy to return to coaching, and to do so at a Premier League club that has the ambition to be a protagonist again.
"Tottenham Hotspur has state-of-the-art facilities and one of the best stadiums in the world.
"I can't wait to start working to convey to the team and the fans the passion, mentality and determination that have always distinguished me, as a player and as a coach.
"Last summer our union did not happen because the end of my relationship with Inter was still too recent and emotionally too involved with the end of the season, so I felt that it wasn't yet the right time to return to coaching.
"But the contagious enthusiasm and determination of Daniel Levy in wanting to entrust me with this task had already hit the mark. Now that the opportunity has returned, I have chosen to take it with great conviction."
Conte will begin his Tottenham career on Thursday when they face Vitesse in the Europa Conference League.
Spurs then make the trip to Everton in the Premier league on Sunday.